Product Data Sheet

E3 ligase Ligand 79

Catalog No. A80443

main product photo
E3 ligase Ligand 79 serves as a ligand for the CRBN E3 ligase, facilitating the development of targeted protein degradation strategies. This compound is crucial for the synthesis of PROTAC CDK2/4 Degrader-1, which allows for selective degradation of protein targets in various biological contexts. Researchers can utilize this ligand to study the mechanisms of E3 ligase-mediated degradation and its potential therapeutic applications.
Chemical Information
Catalog NumA80443
M. Wt258.28
FormulaC13H14N4O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2152672-96-1
Synonyms
SMILESO=C(C(C1=NN(C)C2=C1C=CC(N)=C2)CC3)NC3=O
Biological Activity
DescriptionE3 ligase Ligand 79 serves as a ligand for the CRBN E3 ligase, facilitating the development of targeted protein degradation strategies. This compound is crucial for the synthesis of PROTAC CDK2/4 Degrader-1, which allows for selective degradation of protein targets in various biological contexts. Researchers can utilize this ligand to study the mechanisms of E3 ligase-mediated degradation and its potential therapeutic applications.
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