Product Data Sheet
VH032
Catalog No. A80445
VH032 is a potent ligand for the von Hippel-Lindau (VHL) protein, acting primarily by inhibiting the interaction between VHL and hypoxia-inducible factor 1-alpha (HIF-1α). Its high affinity and specificity make VH032 an essential tool for research applications involving targeted protein degradation through PROTAC technology. This compound facilitates the study of VHL-mediated pathways and the regulation of hypoxic responses in various biological contexts.
Chemical Information
| Catalog Num | A80445 |
|---|---|
| M. Wt | 472.60 |
| Formula | C24H32N4O4S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1448188-62-2 |
| Synonyms | |
| SMILES | CC(N=CS1)=C1C2=CC=C(CNC([C@@H]3C[C@@H](O)CN3C([C@H](C(C)(C)C)NC(C)=O)=O)=O)C=C2 |
Biological Activity
| Description | VH032 is a potent ligand for the von Hippel-Lindau (VHL) protein, acting primarily by inhibiting the interaction between VHL and hypoxia-inducible factor 1-alpha (HIF-1α). Its high affinity and specificity make VH032 an essential tool for research applications involving targeted protein degradation through PROTAC technology. This compound facilitates the study of VHL-mediated pathways and the regulation of hypoxic responses in various biological contexts. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
