Product Data Sheet
(S,R,S)-AHPC-propargyl
Catalog No. A80466
(S,R,S)-AHPC-propargyl is a VHL ligand that serves as a crucial component in the development of PROTACs through its role in "click reactions." This compound features an alkyne functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. Its versatility makes it valuable for drug discovery and chemical biology applications, particularly in the creation of targeted protein degradation strategies.
Chemical Information
| Catalog Num | A80466 |
|---|---|
| M. Wt | 526.65 |
| Formula | C27H34N4O5S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2098799-78-9 |
| Synonyms | VH032-propargyl; VHL ligand 7 |
| SMILES | CC(N=CS1)=C1C2=CC=C(CNC([C@@H]3C[C@@H](O)CN3C([C@@H](NC(COCC#C)=O)C(C)(C)C)=O)=O)C=C2 |
Biological Activity
| Description | (S,R,S)-AHPC-propargyl is a VHL ligand that serves as a crucial component in the development of PROTACs through its role in "click reactions." This compound features an alkyne functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. Its versatility makes it valuable for drug discovery and chemical biology applications, particularly in the creation of targeted protein degradation strategies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
