Product Data Sheet
PD 4'-oxyacetic acid
Catalog No. A80471
PD 4'-oxyacetic acid is a carboxylic acid-functionalized ligand for cereblon, a critical component in the development of PROTAC (Proteolysis Targeting Chimeras) degraders. This compound facilitates targeted protein degradation, making it valuable for research applications focused on protein homeostasis and therapeutic intervention in cancer and other diseases. Its ability to engage with the cereblon E3 ubiquitin ligase complex enhances the potential for novel therapeutic strategies in drug discovery.
Chemical Information
| Catalog Num | A80471 |
|---|---|
| M. Wt | 264.24 |
| Formula | C12H12N2O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2633633-12-0 |
| Synonyms | |
| SMILES | O=C(O)COC1=CC=C(N(C(N2)=O)CCC2=O)C=C1 |
Biological Activity
| Description | PD 4'-oxyacetic acid is a carboxylic acid-functionalized ligand for cereblon, a critical component in the development of PROTAC (Proteolysis Targeting Chimeras) degraders. This compound facilitates targeted protein degradation, making it valuable for research applications focused on protein homeostasis and therapeutic intervention in cancer and other diseases. Its ability to engage with the cereblon E3 ubiquitin ligase complex enhances the potential for novel therapeutic strategies in drug discovery. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
