Product Data Sheet
AR antagonist 1 hydrochloride
Catalog No. A80512
AR Antagonist 1 Hydrochloride is a potent androgen receptor (AR) antagonist that serves as a crucial component in the synthesis of PROTAC ARD-266. It effectively binds to E3 ligase ligands with weak affinities to the VHL protein, facilitating targeted protein degradation. This compound is valuable for research applications focused on AR modulation and targeted therapeutic strategies in prostate cancer and other androgen-related diseases.
Chemical Information
| Catalog Num | A80512 |
|---|---|
| M. Wt | 315.24 |
| Formula | C15H20Cl2N2O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1818885-55-0 |
| Synonyms | |
| SMILES | [H]Cl.N#CC1=CC=C(O[C@H]2C(C)(C)[C@H](N)C2(C)C)C=C1Cl |
Biological Activity
| Description | AR Antagonist 1 Hydrochloride is a potent androgen receptor (AR) antagonist that serves as a crucial component in the synthesis of PROTAC ARD-266. It effectively binds to E3 ligase ligands with weak affinities to the VHL protein, facilitating targeted protein degradation. This compound is valuable for research applications focused on AR modulation and targeted therapeutic strategies in prostate cancer and other androgen-related diseases. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
