Product Data Sheet

Lenalidomide-F

Catalog No. A80514

main product photo
Lenalidomide-F is an E3 ligase ligand that targets cereblon, facilitating the development of PROTAC molecules. It is specifically designed for use with LWY713, a potent degrader of FLT3, exhibiting a DC50 value of 0.64 nM. This compound selectively induces the degradation of FLT3 through proteasome-dependent mechanisms. Lenalidomide-F is valuable for research applications focused on targeted protein degradation and the therapeutic potential of PROTACs in oncology.
Chemical Information
Catalog NumA80514
M. Wt262.24
FormulaC13H11FN2O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2359705-88-5
Synonyms
SMILESO=C(C(N(CC1=C2C=CC=C1F)C2=O)CC3)NC3=O
Biological Activity
DescriptionLenalidomide-F is an E3 ligase ligand that targets cereblon, facilitating the development of PROTAC molecules. It is specifically designed for use with LWY713, a potent degrader of FLT3, exhibiting a DC50 value of 0.64 nM. This compound selectively induces the degradation of FLT3 through proteasome-dependent mechanisms. Lenalidomide-F is valuable for research applications focused on targeted protein degradation and the therapeutic potential of PROTACs in oncology.
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SHIPPING AND STORAGE
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