Product Data Sheet

3-(4-Bromo-2-fluorophenyl)piperidine-2,6-dione

Catalog No. A80541

main product photo
3-(4-Bromo-2-fluorophenyl)piperidine-2,6-dione is an effective ligand for the CRBN-type E3 ubiquitin ligase, facilitating targeted protein degradation through the formation of PROTACs (Proteolysis Targeting Chimeras). This compound is instrumental in studies focused on ubiquitin-mediated proteolysis and can be utilized in various research applications aimed at elucidating protein function and regulation. Its unique structural features enable specific binding interactions that are crucial for the development of innovative therapeutic strategies.
Chemical Information
Catalog NumA80541
M. Wt286.10
FormulaC11H9BrFNO2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2924092-66-8
Synonyms
SMILESO=C1NC(=O)C(C2=CC=C(Br)C=C2F)CC1
Biological Activity
Description3-(4-Bromo-2-fluorophenyl)piperidine-2,6-dione is an effective ligand for the CRBN-type E3 ubiquitin ligase, facilitating targeted protein degradation through the formation of PROTACs (Proteolysis Targeting Chimeras). This compound is instrumental in studies focused on ubiquitin-mediated proteolysis and can be utilized in various research applications aimed at elucidating protein function and regulation. Its unique structural features enable specific binding interactions that are crucial for the development of innovative therapeutic strategies.
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