Product Data Sheet
E3 ligase Ligand 51
Catalog No. A80549
E3 Ligase Ligand 51 functions as a ligand for the E3 ligase CRBN, facilitating targeted protein degradation through the synthesis of PROTACs, specifically BTK Degrader-12. This compound plays a crucial role in the research of protein homeostasis, allowing for the selective degradation of target proteins. Its application is significant in the study of various diseases, including cancer, by modulating protein levels in cellular contexts.
Chemical Information
| Catalog Num | A80549 |
|---|---|
| M. Wt | 301.34 |
| Formula | C16H19N3O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2703915-71-1 |
| Synonyms | |
| SMILES | O=CC1CCN(C2=CC=C(N(C(N3)=O)CCC3=O)C=C2)CC1 |
Biological Activity
| Description | E3 Ligase Ligand 51 functions as a ligand for the E3 ligase CRBN, facilitating targeted protein degradation through the synthesis of PROTACs, specifically BTK Degrader-12. This compound plays a crucial role in the research of protein homeostasis, allowing for the selective degradation of target proteins. Its application is significant in the study of various diseases, including cancer, by modulating protein levels in cellular contexts. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
