Product Data Sheet
SJF-0661
Catalog No. A80550
SJF-0661 is a variant of the von Hippel-Lindau (VHL) protein ligand that lacks the capacity for targeted degradation. Serving as an essential control reagent, it is useful for studies involving VHL ubiquitin ligase ligands. This compound is synthesized by inverting the stereocenter of the critical hydroxyproline moiety in the original VHL ligand, allowing researchers to evaluate the specific activities of VHL ligands in various biological contexts.
Chemical Information
| Catalog Num | A80550 |
|---|---|
| M. Wt | 1010.18 |
| Formula | C51H57F2N9O7S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2413035-43-3 |
| Synonyms | |
| SMILES | O=C(C1=C(C(NS(CCC)(=O)=O)=CC=C1F)F)C2=CNC3=NC=C(C4=CC=C(N5CCN(CC5)CC(N[C@@H](C(C)(C)C)C(N6[C@@H](C[C@@H](C6)O)C(NCC7=CC=C(C8=C(C)N=CS8)C=C7)=O)=O)=O)C=C4)C=C23 |
Biological Activity
| Description | SJF-0661 is a variant of the von Hippel-Lindau (VHL) protein ligand that lacks the capacity for targeted degradation. Serving as an essential control reagent, it is useful for studies involving VHL ubiquitin ligase ligands. This compound is synthesized by inverting the stereocenter of the critical hydroxyproline moiety in the original VHL ligand, allowing researchers to evaluate the specific activities of VHL ligands in various biological contexts. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
