Product Data Sheet
AR antagonist 1
Catalog No. A80557
AR Antagonist 1 is a potent androgen receptor (AR) antagonist that serves as a key PROTAC ligand. It demonstrates significant activity in disrupting AR signaling pathways, making it valuable for research into androgen-related diseases. Additionally, it has weak binding affinities to VHL protein, facilitating the synthesis of PROTAC ARD-266 for studying targeted protein degradation mechanisms in cancer and other therapeutic areas.
Chemical Information
| Catalog Num | A80557 |
|---|---|
| M. Wt | 278.78 |
| Formula | C15H19ClN2O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1818885-54-9 |
| Synonyms | |
| SMILES | N#CC1=CC=C(O[C@H]2C(C)(C)[C@H](N)C2(C)C)C=C1Cl |
Biological Activity
| Description | AR Antagonist 1 is a potent androgen receptor (AR) antagonist that serves as a key PROTAC ligand. It demonstrates significant activity in disrupting AR signaling pathways, making it valuable for research into androgen-related diseases. Additionally, it has weak binding affinities to VHL protein, facilitating the synthesis of PROTAC ARD-266 for studying targeted protein degradation mechanisms in cancer and other therapeutic areas. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
