Product Data Sheet

Thalidomide-4-carbaldehyde

Catalog No. A80571

main product photo
Thalidomide-4-carbaldehyde is a Thalidomide analogue featuring an aldehyde functional group. This compound is known to recruit E3 ligases, facilitating the ubiquitination and subsequent proteolysis of target proteins, making it a valuable tool in studying protein degradation pathways. Its highly reactive aldehyde group engages in reductive amination reactions with amine nucleophiles, offering diverse applications in chemical biology and medicinal chemistry research.
Chemical Information
Catalog NumA80571
M. Wt286.24
FormulaC14H10N2O5
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2369068-46-0
Synonyms
SMILESO=CC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O
Biological Activity
DescriptionThalidomide-4-carbaldehyde is a Thalidomide analogue featuring an aldehyde functional group. This compound is known to recruit E3 ligases, facilitating the ubiquitination and subsequent proteolysis of target proteins, making it a valuable tool in studying protein degradation pathways. Its highly reactive aldehyde group engages in reductive amination reactions with amine nucleophiles, offering diverse applications in chemical biology and medicinal chemistry research.
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