(R,S,S)-VH032-Me
Catalog No. A80597

(R,S,S)-VH032-Me is a ligand for E3 ubiquitin ligase, playing a crucial role in targeted protein degradation through the ubiquitin-proteasome pathway. It can be conjugated to proteins via a linker to create PROTACs such as dTAGV-1-NEG, which facilitate the selective degradation of oncogenic proteins. This compound is essential for studies involving targeted protein degradation, offering valuable insights into cancer biology and therapeutic development.
| Catalog Num | A80597 |
|---|---|
| M. Wt | 444.59 |
| Formula | C23H32N4O3S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1948273-05-9 |
| Synonyms | |
| SMILES | N[C@H](C(N1[C@H](C[C@@H](C1)O)C(N[C@@H](C)C2=CC=C(C=C2)C3=C(N=CS3)C)=O)=O)C(C)(C)C |
| Description | (R,S,S)-VH032-Me is a ligand for E3 ubiquitin ligase, playing a crucial role in targeted protein degradation through the ubiquitin-proteasome pathway. It can be conjugated to proteins via a linker to create PROTACs such as dTAGV-1-NEG, which facilitate the selective degradation of oncogenic proteins. This compound is essential for studies involving targeted protein degradation, offering valuable insights into cancer biology and therapeutic development. |
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