Product Data Sheet
Pomalidomide-5-O-CH3
Catalog No. A80598
Pomalidomide-5-O-CH3 is a synthetic derivative of Pomalidomide designed as a ligand for cereblon (CRBN), an E3 ubiquitin ligase. This compound facilitates the recruitment of CRBN, enabling targeted protein degradation through PROTAC (proteolysis targeting chimeras) technology. Pomalidomide-5-O-CH3 is valuable for research in targeted therapy and ubiquitin-proteasome system studies, contributing to insights in cancer treatment and cellular regulation.
Chemical Information
| Catalog Num | A80598 |
|---|---|
| M. Wt | 303.27 |
| Formula | C14H13N3O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1547163-02-9 |
| Synonyms | |
| SMILES | O=C1C2=CC=C(C(N)=C2C(N1C3C(NC(CC3)=O)=O)=O)OC |
Biological Activity
| Description | Pomalidomide-5-O-CH3 is a synthetic derivative of Pomalidomide designed as a ligand for cereblon (CRBN), an E3 ubiquitin ligase. This compound facilitates the recruitment of CRBN, enabling targeted protein degradation through PROTAC (proteolysis targeting chimeras) technology. Pomalidomide-5-O-CH3 is valuable for research in targeted therapy and ubiquitin-proteasome system studies, contributing to insights in cancer treatment and cellular regulation. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
