Product Data Sheet
VH032 analogue-2
Catalog No. A80618
VH032 analogue-2 is a selective ligand for the E3 ubiquitin ligase von Hippel-Lindau (VHL), facilitating its recruitment in cellular processes. This compound effectively removes its protective group under acidic conditions, enabling its direct utilization in the synthesis of PROTAC (Proteolysis Targeting Chimeras) molecules. VH032 analogue-2 serves as a crucial intermediate for the development of VHL-based PROTACs, making it a valuable tool for research in targeted protein degradation and related fields.
Chemical Information
| Catalog Num | A80618 |
|---|---|
| M. Wt | 516.65 |
| Formula | C26H36N4O5S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1448189-66-9 |
| Synonyms | |
| SMILES | O=C(NCC1=CC=C(C2=C(C)N=CS2)C=C1)[C@H]3N(C([C@H](C(C)C)NC(OC(C)(C)C)=O)=O)C[C@H](O)C3 |
Biological Activity
| Description | VH032 analogue-2 is a selective ligand for the E3 ubiquitin ligase von Hippel-Lindau (VHL), facilitating its recruitment in cellular processes. This compound effectively removes its protective group under acidic conditions, enabling its direct utilization in the synthesis of PROTAC (Proteolysis Targeting Chimeras) molecules. VH032 analogue-2 serves as a crucial intermediate for the development of VHL-based PROTACs, making it a valuable tool for research in targeted protein degradation and related fields. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
