Product Data Sheet
E3 ligase Ligand 21
Catalog No. A80622
E3 ligase Ligand 21 is a potent cereblon binder that facilitates the targeted degradation of Ikaros and Aiolos via the ubiquitin-proteasome pathway. This compound is valuable for research applications focusing on the modulation of transcription factors involved in hematologic malignancies and immune regulation. Its ability to selectively promote protein degradation makes it an important tool in the study of cellular homeostasis and targeted therapy development.
Chemical Information
| Catalog Num | A80622 |
|---|---|
| M. Wt | 525.64 |
| Formula | C31H35N5O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2504233-73-0 |
| Synonyms | |
| SMILES | O=C1C2=CC=CC3=C2C(N1C4C(NC(CC4)=O)=O)=CC=C3CC5=CN(C6CCN(CC7(CCC7)C)CC6)N=C5 |
Biological Activity
| Description | E3 ligase Ligand 21 is a potent cereblon binder that facilitates the targeted degradation of Ikaros and Aiolos via the ubiquitin-proteasome pathway. This compound is valuable for research applications focusing on the modulation of transcription factors involved in hematologic malignancies and immune regulation. Its ability to selectively promote protein degradation makes it an important tool in the study of cellular homeostasis and targeted therapy development. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
