Product Data Sheet
VHL-SF2
Catalog No. A80667
VHL-SF2 is a selective ligand for the von Hippel-Lindau (VHL) protein, facilitating the synthesis of PROTACs (proteolysis-targeting chimeras). By engaging the VHL E3 ubiquitin ligase, VHL-SF2 promotes the targeted degradation of specific proteins, making it a valuable tool in drug discovery and development. This compound is essential for researchers investigating targeted protein degradation and enhancing the therapeutic potential of protein-based treatments.
Chemical Information
| Catalog Num | A80667 |
|---|---|
| M. Wt | 662.79 |
| Formula | C31H39FN4O7S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3050690-24-6 |
| Synonyms | |
| SMILES | CC(C)[C@H](C1=CC(C)=NO1)C(N2[C@@H](C[C@H](C2)S(F)(=O)=O)C(N[C@H](C3=CC=C(C4=C(N=CS4)C)C=C3)CC(OC(C)(C)C)=O)=O)=O |
Biological Activity
| Description | VHL-SF2 is a selective ligand for the von Hippel-Lindau (VHL) protein, facilitating the synthesis of PROTACs (proteolysis-targeting chimeras). By engaging the VHL E3 ubiquitin ligase, VHL-SF2 promotes the targeted degradation of specific proteins, making it a valuable tool in drug discovery and development. This compound is essential for researchers investigating targeted protein degradation and enhancing the therapeutic potential of protein-based treatments. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
