Product Data Sheet
E3 ligase Ligand 49
Catalog No. A80670
E3 ligase Ligand 49 is an E3 ubiquitin ligase ligand that plays a critical role in the development of PROTAC (Proteolysis Targeting Chimeras) technology. This compound is specifically designed for the synthesis of PROTACs targeting XPO1, facilitating targeted protein degradation in various biological contexts. Its application is particularly relevant in studies focusing on protein regulation and degradation pathways, providing valuable insights into cellular processes and disease mechanisms.
Chemical Information
| Catalog Num | A80670 |
|---|---|
| M. Wt | 277.28 |
| Formula | C13H15N3O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1911013-66-5 |
| Synonyms | |
| SMILES | COC1=C(C(NC2C(NC(CC2)=O)=O)=O)C=CC=C1N |
Biological Activity
| Description | E3 ligase Ligand 49 is an E3 ubiquitin ligase ligand that plays a critical role in the development of PROTAC (Proteolysis Targeting Chimeras) technology. This compound is specifically designed for the synthesis of PROTACs targeting XPO1, facilitating targeted protein degradation in various biological contexts. Its application is particularly relevant in studies focusing on protein regulation and degradation pathways, providing valuable insights into cellular processes and disease mechanisms. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
