Product Data Sheet
Thalidomide-5-Br,6-F
Catalog No. A80744
Thalidomide-5-Br,6-F is a Thalidomide analogue functioning as an E3 ligase activator, promoting the ubiquitination of target proteins for proteolytic degradation. This compound enhances cellular pathways by modulating protein turnover, making it valuable in studies related to protein homeostasis and targeted degradation. Its unique structural features allow for potential further derivatization through substitution at the fluorine or bromine positions, offering avenues for the development of novel reagents.
Chemical Information
| Catalog Num | A80744 |
|---|---|
| M. Wt | 355.12 |
| Formula | C13H8BrFN2O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2803445-69-2 |
| Synonyms | |
| SMILES | O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=C(F)C(Br)=C3)=O |
Biological Activity
| Description | Thalidomide-5-Br,6-F is a Thalidomide analogue functioning as an E3 ligase activator, promoting the ubiquitination of target proteins for proteolytic degradation. This compound enhances cellular pathways by modulating protein turnover, making it valuable in studies related to protein homeostasis and targeted degradation. Its unique structural features allow for potential further derivatization through substitution at the fluorine or bromine positions, offering avenues for the development of novel reagents. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
