Product Data Sheet
5-(2-Chloroacetamide) thalidomide
Catalog No. A80752
5-(2-Chloroacetamide) thalidomide is a Thalidomide analog that functions as an E3 ligase recruiter, facilitating the ubiquitination and targeted degradation of specific proteins. The inclusion of a chloroacetamide moiety enhances its reactivity towards thiol groups, potentially increasing its efficacy in modulating protein degradation pathways. This compound is of interest for research applications in targeted protein therapy and cancer biology, providing insights into the mechanisms of protein homeostasis.
Chemical Information
| Catalog Num | A80752 |
|---|---|
| M. Wt | 349.73 |
| Formula | C15H12ClN3O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1957235-51-6 |
| Synonyms | |
| SMILES | ClCC(NC1=CC=C2C(N(C(C2=C1)=O)C3CCC(NC3=O)=O)=O)=O |
Biological Activity
| Description | 5-(2-Chloroacetamide) thalidomide is a Thalidomide analog that functions as an E3 ligase recruiter, facilitating the ubiquitination and targeted degradation of specific proteins. The inclusion of a chloroacetamide moiety enhances its reactivity towards thiol groups, potentially increasing its efficacy in modulating protein degradation pathways. This compound is of interest for research applications in targeted protein therapy and cancer biology, providing insights into the mechanisms of protein homeostasis. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
