Product Data Sheet
CRBN ligand-298
Catalog No. A80762
CRBN ligand-298 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), enabling the selective recruitment of CRBN to target proteins. By facilitating the formation of a PROTAC (proteolysis-targeting chimera), CRBN ligand-298 functions to promote targeted protein degradation, making it a valuable tool for studies in protein regulation and therapeutic development. This reagent is essential for researchers investigating the therapeutic potential of targeted protein degradation pathways.
Chemical Information
| Catalog Num | A80762 |
|---|---|
| M. Wt | 308.14 |
| Formula | C12H10BrN3O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2925082-11-5 |
| Synonyms | |
| SMILES | O=C1NC(=O)CCN1C2=CC=C(Br)C=3NC=CC23 |
Biological Activity
| Description | CRBN ligand-298 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), enabling the selective recruitment of CRBN to target proteins. By facilitating the formation of a PROTAC (proteolysis-targeting chimera), CRBN ligand-298 functions to promote targeted protein degradation, making it a valuable tool for studies in protein regulation and therapeutic development. This reagent is essential for researchers investigating the therapeutic potential of targeted protein degradation pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
