Product Data Sheet

CRBN ligand-507

Catalog No. A80818

main product photo
CRBN ligand-507 functions as a ligand for the E3 ubiquitin ligase cereblon (CRBN). This compound facilitates the recruitment of the cereblon protein, making it a valuable tool in targeted protein degradation research. CRBN ligand-507 can be conjugated to a target-specific ligand through a linker, enabling the creation of PROTACs for the selective degradation of intracellular proteins. Its applications include studying protein turnover and modulation of cellular pathways.
Chemical Information
Catalog NumA80818
M. Wt269.26
FormulaC14H11N3O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2925088-55-5
Synonyms
SMILESO=CC1=CC=C(C=2C=CN=CC12)N3C(=O)NC(=O)CC3
Biological Activity
DescriptionCRBN ligand-507 functions as a ligand for the E3 ubiquitin ligase cereblon (CRBN). This compound facilitates the recruitment of the cereblon protein, making it a valuable tool in targeted protein degradation research. CRBN ligand-507 can be conjugated to a target-specific ligand through a linker, enabling the creation of PROTACs for the selective degradation of intracellular proteins. Its applications include studying protein turnover and modulation of cellular pathways.
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