Product Data Sheet
CRBN ligand-549
Catalog No. A80834
CRBN ligand-549 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN), which facilitates the recruitment of CRBN to target proteins. This compound can be utilized in the design and synthesis of PROTACs (proteolysis-targeting chimeras), enabling targeted degradation of specific proteins within cellular pathways. Researchers can apply CRBN ligand-549 in studies aimed at understanding protein turnover, modulation of signaling pathways, and therapeutic development for various diseases.
Chemical Information
| Catalog Num | A80834 |
|---|---|
| M. Wt | 286.25 |
| Formula | C13H10N4O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2925102-78-7 |
| Synonyms | |
| SMILES | O=C(O)C1=CC=2C=NC=NC2C(=C1)N3C(=O)NC(=O)CC3 |
Biological Activity
| Description | CRBN ligand-549 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN), which facilitates the recruitment of CRBN to target proteins. This compound can be utilized in the design and synthesis of PROTACs (proteolysis-targeting chimeras), enabling targeted degradation of specific proteins within cellular pathways. Researchers can apply CRBN ligand-549 in studies aimed at understanding protein turnover, modulation of signaling pathways, and therapeutic development for various diseases. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
