Product Data Sheet
Thalidomide-5-(C6-amine)
Catalog No. A80878
Thalidomide-5-(C6-amine) is a thalidomide analogue functioning as a PROTAC building block, featuring an E3 ligase ligand with a terminal amine group. This amine group facilitates conjugation reactions with NHS ester groups or carboxylic acids in the presence of coupling agents such as EDC or HATU. Thalidomide-5-(C6-amine) is valuable in the development of bifunctional degraders, supporting research in targeted protein degradation and therapeutic interventions.
Chemical Information
| Catalog Num | A80878 |
|---|---|
| M. Wt | 400.43 |
| Formula | C20H24N4O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1950635-17-2 |
| Synonyms | |
| SMILES | NCCCCCCNC(C1=CC=C2C(N(C(C2=C1)=O)C3CCC(NC3=O)=O)=O)=O |
Biological Activity
| Description | Thalidomide-5-(C6-amine) is a thalidomide analogue functioning as a PROTAC building block, featuring an E3 ligase ligand with a terminal amine group. This amine group facilitates conjugation reactions with NHS ester groups or carboxylic acids in the presence of coupling agents such as EDC or HATU. Thalidomide-5-(C6-amine) is valuable in the development of bifunctional degraders, supporting research in targeted protein degradation and therapeutic interventions. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
