Product Data Sheet

Desamino lenalidomide-4-F-7-Br

Catalog No. A81003

main product photo
Desamino lenalidomide-4-F-7-Br is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN). This compound facilitates the recruitment of CRBN, enabling targeted protein degradation through the formation of PROTACs when linked with a target protein ligand. Its application in research includes investigating the role of CRBN in various cellular processes and potential therapeutic strategies in cancer and other diseases.
Chemical Information
Catalog NumA81003
M. Wt341.14
FormulaC13H10BrFN2O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2438243-28-6
Synonyms
SMILESO=C1NC(=O)C(N2C(=O)C=3C(Br)=CC=C(F)C3C2)CC1
Biological Activity
DescriptionDesamino lenalidomide-4-F-7-Br is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN). This compound facilitates the recruitment of CRBN, enabling targeted protein degradation through the formation of PROTACs when linked with a target protein ligand. Its application in research includes investigating the role of CRBN in various cellular processes and potential therapeutic strategies in cancer and other diseases.
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