Product Data Sheet
Thalidomide-Piperazine-PEG2-NH2 hydrochloride
Catalog No. A81005
Thalidomide-Piperazine-PEG2-NH2 hydrochloride is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. This compound can be utilized in the development of PROTACs by linking it to a target protein ligand via a suitable linker, thus advancing research in targeted protein degradation and related therapeutic applications. Its ability to modulate protein levels makes it a valuable tool in cellular and molecular biology studies.
Chemical Information
| Catalog Num | A81005 |
|---|---|
| M. Wt | 509.99 |
| Formula | C23H32ClN5O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2357110-15-5 |
| Synonyms | |
| SMILES | Cl.O=C1C2=CC=C(C=C2C(=O)N1C3C(=O)NC(=O)CC3)N4CCN(CCOCCOCCN)CC4 |
Biological Activity
| Description | Thalidomide-Piperazine-PEG2-NH2 hydrochloride is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. This compound can be utilized in the development of PROTACs by linking it to a target protein ligand via a suitable linker, thus advancing research in targeted protein degradation and related therapeutic applications. Its ability to modulate protein levels makes it a valuable tool in cellular and molecular biology studies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
