Product Data Sheet
CRBN ligand-45
Catalog No. A81011
CRBN ligand-45 functions as a ligand for the CRBN-type E3 ubiquitin ligase, facilitating targeted protein degradation through the proteolysis-targeting chimera (PROTAC) technology. This compound is essential for research applications focused on investigating ubiquitination pathways and developing novel therapeutic strategies that harness the ubiquitin-proteasome system. Its ability to selectively engage E3 ligases makes it a valuable tool in the study of cellular protein homeostasis and degradation mechanisms.
Chemical Information
| Catalog Num | A81011 |
|---|---|
| M. Wt | 286.10 |
| Formula | C11H9BrFNO2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3065496-78-5 |
| Synonyms | |
| SMILES | O=C(CCC1C2=CC(Br)=CC=C2F)NC1=O |
Biological Activity
| Description | CRBN ligand-45 functions as a ligand for the CRBN-type E3 ubiquitin ligase, facilitating targeted protein degradation through the proteolysis-targeting chimera (PROTAC) technology. This compound is essential for research applications focused on investigating ubiquitination pathways and developing novel therapeutic strategies that harness the ubiquitin-proteasome system. Its ability to selectively engage E3 ligases makes it a valuable tool in the study of cellular protein homeostasis and degradation mechanisms. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
