CRBN ligand-16
Catalog No. A81032

CRBN ligand-16 is a ligand for the E3 ubiquitin ligase CRBN, enabling targeted protein degradation through the formation of PROTAC molecules. This compound facilitates the ubiquitination and subsequent proteasomal degradation of specific proteins, offering valuable applications in drug development and disease research. Its utility in creating bifunctional degradation agents makes it a crucial tool for studies involving protein modulation and therapeutic interventions.
Chemical Information
| Catalog Num | A81032 |
|---|---|
| M. Wt | 282.13 |
| Formula | C12H12BrNO2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3050687-81-2 |
| Synonyms | |
| SMILES | BrC1=CC=CC(C2CCC(NC2=O)=O)=C1C |
Biological Activity
| Description | CRBN ligand-16 is a ligand for the E3 ubiquitin ligase CRBN, enabling targeted protein degradation through the formation of PROTAC molecules. This compound facilitates the ubiquitination and subsequent proteasomal degradation of specific proteins, offering valuable applications in drug development and disease research. Its utility in creating bifunctional degradation agents makes it a crucial tool for studies involving protein modulation and therapeutic interventions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


