Product Data Sheet

CRBN ligand-413

Catalog No. A81062

main product photo
CRBN ligand-413 is an E3 ubiquitin ligase ligand that specifically targets cereblon (CRBN). This compound facilitates the recruitment of the CRBN protein and can be utilized in the development of PROTACs by linking it to a target protein ligand through a suitable linker. Its applications are significant in studying targeted protein degradation and the modulation of protein levels within cellular contexts.
Chemical Information
Catalog NumA81062
M. Wt269.26
FormulaC14H11N3O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2925101-91-1
Synonyms
SMILESO=CC1=CN=C2C=CC=C(C2=C1)N3C(=O)NC(=O)CC3
Biological Activity
DescriptionCRBN ligand-413 is an E3 ubiquitin ligase ligand that specifically targets cereblon (CRBN). This compound facilitates the recruitment of the CRBN protein and can be utilized in the development of PROTACs by linking it to a target protein ligand through a suitable linker. Its applications are significant in studying targeted protein degradation and the modulation of protein levels within cellular contexts.
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