Product Data Sheet
Thalidomide-pinacolborane
Catalog No. A81079
Thalidomide-pinacolborane is a Thalidomide analogue that incorporates a boronic pinacol ester (Bpin group) and serves as an activator for E3 ligases. This compound plays a crucial role in ubiquitination, facilitating the targeted degradation of proteins through proteolytic pathways. Its applications in chemical biology include studies on protein regulation and modulation of cellular signaling processes, making it a valuable tool in research focused on proteostasis and therapeutic interventions.
Chemical Information
| Catalog Num | A81079 |
|---|---|
| M. Wt | 384.19 |
| Formula | C19H21BN2O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2229725-98-6 |
| Synonyms | |
| SMILES | O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC(B4OC(C)(C)C(C)(C)O4)=C3)=O |
Biological Activity
| Description | Thalidomide-pinacolborane is a Thalidomide analogue that incorporates a boronic pinacol ester (Bpin group) and serves as an activator for E3 ligases. This compound plays a crucial role in ubiquitination, facilitating the targeted degradation of proteins through proteolytic pathways. Its applications in chemical biology include studies on protein regulation and modulation of cellular signaling processes, making it a valuable tool in research focused on proteostasis and therapeutic interventions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
