Product Data Sheet
CRBN ligand-553
Catalog No. A81096
CRBN ligand-553 is a specific ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. It can be utilized to conjugate with target protein ligands via a linker to create Proteolysis Targeting Chimeras (PROTACs). This compound is crucial for studying targeted protein degradation and has applications in drug development and cellular biology research.
Chemical Information
| Catalog Num | A81096 |
|---|---|
| M. Wt | 323.15 |
| Formula | C12H11BrN4O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2925100-20-3 |
| Synonyms | |
| SMILES | O=C1NC(=O)CCN1C=2C=C(Br)C3=C(C=NN3C)C2 |
Biological Activity
| Description | CRBN ligand-553 is a specific ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. It can be utilized to conjugate with target protein ligands via a linker to create Proteolysis Targeting Chimeras (PROTACs). This compound is crucial for studying targeted protein degradation and has applications in drug development and cellular biology research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
