NH2-MeO-Ph-amide-(2,6-Dioxo-3-Pip)
Catalog No. A81146

NH2-MeO-Ph-amide-(2,6-Dioxo-3-Pip) is a ligand that targets Cereblon (CRBN), a key component of the E3 ubiquitin ligase complex. This compound facilitates the synthesis of PROTAC BRD4 Degrader-22, enabling targeted degradation of the BRD4 protein. Its applications include research in the field of protein degradation and regulation of gene expression, providing a valuable tool for studying the role of BRD4 in various biological processes.
Chemical Information
| Catalog Num | A81146 |
|---|---|
| M. Wt | 277.28 |
| Formula | C13H15N3O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1504209-32-8 |
| Synonyms | |
| SMILES | O=C(NC(CC1)C(NC1=O)=O)C2=CC=C(N)C=C2OC |
Biological Activity
| Description | NH2-MeO-Ph-amide-(2,6-Dioxo-3-Pip) is a ligand that targets Cereblon (CRBN), a key component of the E3 ubiquitin ligase complex. This compound facilitates the synthesis of PROTAC BRD4 Degrader-22, enabling targeted degradation of the BRD4 protein. Its applications include research in the field of protein degradation and regulation of gene expression, providing a valuable tool for studying the role of BRD4 in various biological processes. |
|---|
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


