Tetrafluoro-thalidomide
Catalog No. A81169

Tetrafluoro-thalidomide is a fluorinated analogue of thalidomide, targeting E3 ligases to activate ubiquitination of proteins for subsequent proteolysis. This compound shows potential significance in studying protein degradation pathways and the therapeutic implications of inhibiting or enhancing E3 ligase activity. Its unique fluorinated structure allows for further derivatization, facilitating the exploration of novel compounds in chemical biology and drug development applications.
Chemical Information
| Catalog Num | A81169 |
|---|---|
| M. Wt | 330.19 |
| Formula | C13H6F4N2O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 179033-21-7 |
| Synonyms | |
| SMILES | O=C1C2=C(C(N1C3C(NC(CC3)=O)=O)=O)C(F)=C(F)C(F)=C2F |
Biological Activity
| Description | Tetrafluoro-thalidomide is a fluorinated analogue of thalidomide, targeting E3 ligases to activate ubiquitination of proteins for subsequent proteolysis. This compound shows potential significance in studying protein degradation pathways and the therapeutic implications of inhibiting or enhancing E3 ligase activity. Its unique fluorinated structure allows for further derivatization, facilitating the exploration of novel compounds in chemical biology and drug development applications. |
|---|
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


