Product Data Sheet
CRBN ligand-667
Catalog No. A81261
CRBN ligand-667 is a potent ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of this protein for targeted protein degradation. When conjugated with a specific target protein ligand through a linker, CRBN ligand-667 can be utilized to construct a PROTAC, enabling controlled degradation of the target protein. This compound is valuable for research applications focused on protein homeostasis, cellular regulation, and therapeutic development in oncology and other diseases.
Chemical Information
| Catalog Num | A81261 |
|---|---|
| M. Wt | 245.28 |
| Formula | C13H15N3O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2925088-10-2 |
| Synonyms | |
| SMILES | O=C1NC(=O)CCN1C2=CC=CC3=C2CCNC3 |
Biological Activity
| Description | CRBN ligand-667 is a potent ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of this protein for targeted protein degradation. When conjugated with a specific target protein ligand through a linker, CRBN ligand-667 can be utilized to construct a PROTAC, enabling controlled degradation of the target protein. This compound is valuable for research applications focused on protein homeostasis, cellular regulation, and therapeutic development in oncology and other diseases. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
