Product Data Sheet
Tri-GalNAc-DBCO
Catalog No. A81373
Tri-GalNAc-DBCO is a synthetic ligand featuring three GalNAc units linked to DBCO, designed for use in protein degradation applications. It selectively targets the asialoglycoprotein receptor (ASGPR), facilitating the delivery of conjugated proteins or small molecules to lysosomes via receptor-mediated endocytosis. This targeted approach allows for the effective degradation of substrates, making Tri-GalNAc-DBCO a valuable tool in research focusing on lysosomal-targeted therapeutics and protein modulation strategies.
Chemical Information
| Catalog Num | A81373 |
|---|---|
| M. Wt | 1730.94 |
| Formula | C82H127N11O29 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2999748-27-3 |
| Synonyms | |
| SMILES | O=C(NCCCNC(CCCCO[C@H](O[C@@H]1CO)[C@@H]([C@H]([C@H]1O)O)NC(C)=O)=O)CCOCC(COCCC(NCCCNC(CCCCO[C@H](O[C@@H]2CO)[C@@H]([C@H]([C@H]2O)O)NC(C)=O)=O)=O)(NC(CCCCC(N3CC4=CC=CC=C4C#CC5=CC=CC=C53)=O)=O)COCCC(NCCCNC(CCCCO[C@H](O[C@@H]6CO)[C@@H]([C@H]([C@H]6O)O)NC(C)=O)=O)=O |
Biological Activity
| Description | Tri-GalNAc-DBCO is a synthetic ligand featuring three GalNAc units linked to DBCO, designed for use in protein degradation applications. It selectively targets the asialoglycoprotein receptor (ASGPR), facilitating the delivery of conjugated proteins or small molecules to lysosomes via receptor-mediated endocytosis. This targeted approach allows for the effective degradation of substrates, making Tri-GalNAc-DBCO a valuable tool in research focusing on lysosomal-targeted therapeutics and protein modulation strategies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
