Product Data Sheet
GR–14-3-3 stabilizer-1
Catalog No. A81400
GR-14-3-3 stabilizer-1 is a molecular glue stabilizer that effectively enhances the stability of glucocorticoid receptors (GR) by preventing their interaction with 14-3-3 proteins. This compound is instrumental in research involving the modulation of GR signaling pathways, providing a valuable tool for studying glucocorticoid-related cellular responses and their implications in various disease states. Its applications extend to the development of novel therapeutic strategies targeting GR dynamics in cellular contexts.
Chemical Information
| Catalog Num | A81400 |
|---|---|
| M. Wt | 317.79 |
| Formula | C15H12ClN3OS |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 271798-59-5 |
| Synonyms | |
| SMILES | O=C1NN=C(CSC2=CC=C(C=C2)Cl)N1C3=CC=CC=C3 |
Biological Activity
| Description | GR-14-3-3 stabilizer-1 is a molecular glue stabilizer that effectively enhances the stability of glucocorticoid receptors (GR) by preventing their interaction with 14-3-3 proteins. This compound is instrumental in research involving the modulation of GR signaling pathways, providing a valuable tool for studying glucocorticoid-related cellular responses and their implications in various disease states. Its applications extend to the development of novel therapeutic strategies targeting GR dynamics in cellular contexts. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
