Product Data Sheet
5-Ethynyl-2'-deoxyuridine
Catalog No. A81424
5-Ethynyl-2'-deoxyuridine (EdU) is a thymidine analogue that serves as a vital tool in cell proliferation studies. This compound can be incorporated into cellular DNA during replication and subsequently reacts with a fluorescent azide through a copper-catalyzed azide-alkyne cycloaddition (CuAAc) “Click” reaction, allowing for advanced imaging techniques. EdU also functions as an alkyl chain-based linker for the synthesis of PROTACs, facilitating targeted protein degradation in research applications. Its unique properties make it essential for investigations in cellular dynamics and innovative therapeutic strategies.
Chemical Information
| Catalog Num | A81424 |
|---|---|
| M. Wt | 252.23 |
| Formula | C11H12N2O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 61135-33-9 |
| Synonyms | EdU |
| SMILES | O[C@H]1C[C@H](N2C(NC(C(C#C)=C2)=O)=O)O[C@@H]1CO |
Biological Activity
| Description | 5-Ethynyl-2'-deoxyuridine (EdU) is a thymidine analogue that serves as a vital tool in cell proliferation studies. This compound can be incorporated into cellular DNA during replication and subsequently reacts with a fluorescent azide through a copper-catalyzed azide-alkyne cycloaddition (CuAAc) “Click” reaction, allowing for advanced imaging techniques. EdU also functions as an alkyl chain-based linker for the synthesis of PROTACs, facilitating targeted protein degradation in research applications. Its unique properties make it essential for investigations in cellular dynamics and innovative therapeutic strategies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
