Product Data Sheet
Amino-PEG3-C2-Azido
Catalog No. A81438
Amino-PEG3-C2-Azido is a PEG-based linker designed for use in PROTAC applications, facilitating the synthesis of targeted protein degraders, such as the PARP1 degrader iRucaparib-TP3. This compound features an azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-bearing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN functionalized compounds, making it a versatile tool for chemical biology and drug discovery research.
Chemical Information
| Catalog Num | A81438 |
|---|---|
| M. Wt | 218.25 |
| Formula | C8H18N4O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 134179-38-7 |
| Synonyms | |
| SMILES | [N-]=[N+]=NCCOCCOCCOCCN |
Biological Activity
| Description | Amino-PEG3-C2-Azido is a PEG-based linker designed for use in PROTAC applications, facilitating the synthesis of targeted protein degraders, such as the PARP1 degrader iRucaparib-TP3. This compound features an azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-bearing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN functionalized compounds, making it a versatile tool for chemical biology and drug discovery research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
