Product Data Sheet

Biotin alkyne

Catalog No. A81440

main product photo
Biotin alkyne is a PEG-based linker designed for the synthesis of PROTACs, targeting the ubiquitin-proteasome system. As a click chemistry reagent, it features an alkyne group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAC) with azide-containing molecules. This functionality facilitates the efficient assembly of bifunctional degraders, advancing research in targeted protein degradation and therapeutic development.
Chemical Information
Catalog NumA81440
M. Wt281.37
FormulaC13H19N3O2S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.773888-45-2
Synonyms
SMILESO=C(NCC#C)CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O
Biological Activity
DescriptionBiotin alkyne is a PEG-based linker designed for the synthesis of PROTACs, targeting the ubiquitin-proteasome system. As a click chemistry reagent, it features an alkyne group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAC) with azide-containing molecules. This functionality facilitates the efficient assembly of bifunctional degraders, advancing research in targeted protein degradation and therapeutic development.
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SHIPPING AND STORAGE
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