Biotin-PEG4-alkyne
Catalog No. A81442

Biotin-PEG4-alkyne is a biotin-functionalized linker designed for use in the synthesis of PROTACs, targeting protein degradation pathways. This PEG-based compound features an alkyne functional group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc), enabling the efficient conjugation with azide-containing molecules. Its application is vital in developing PROTACs for targeted protein degradation studies and therapeutic interventions.
Chemical Information
| Catalog Num | A81442 |
|---|---|
| M. Wt | 457.58 |
| Formula | C21H35N3O6S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1458576-00-5 |
| Synonyms | |
| SMILES | O=C(NCCOCCOCCOCCOCC#C)CCCC[C@H]1SC[C@@]([C@@]1([H])N2)([H])NC2=O |
Biological Activity
| Description | Biotin-PEG4-alkyne is a biotin-functionalized linker designed for use in the synthesis of PROTACs, targeting protein degradation pathways. This PEG-based compound features an alkyne functional group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc), enabling the efficient conjugation with azide-containing molecules. Its application is vital in developing PROTACs for targeted protein degradation studies and therapeutic interventions. |
|---|
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


