Product Data Sheet

DBCO-Biotin

Catalog No. A81459

main product photo
DBCO-Biotin is a PROTAC linker featuring an alkyl chain structure that facilitates the synthesis of PROTACs. As a click chemistry reagent, it contains a DBCO moiety that efficiently undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. This property makes DBCO-Biotin a valuable tool in targeted protein degradation research, allowing for the precise construction of bifunctional compounds necessary for therapeutic development.
Chemical Information
Catalog NumA81459
M. Wt502.63
FormulaC28H30N4O3S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1418217-95-4
Synonyms
SMILESO=C1N[C@](CS2)([H])[C@@](N1)([H])[C@@H]2CCCCC(NCCC(N3C4=CC=CC=C4C#CC5=CC=CC=C5C3)=O)=O
Biological Activity
DescriptionDBCO-Biotin is a PROTAC linker featuring an alkyl chain structure that facilitates the synthesis of PROTACs. As a click chemistry reagent, it contains a DBCO moiety that efficiently undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. This property makes DBCO-Biotin a valuable tool in targeted protein degradation research, allowing for the precise construction of bifunctional compounds necessary for therapeutic development.
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SHIPPING AND STORAGE
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