Product Data Sheet
Azido-PEG1-CH2CO2H
Catalog No. A81498
Azido-PEG1-CH2CO2H is a PROTAC linker designed to facilitate targeted protein degradation through its alkyl/ether structure. This compound acts as a versatile click chemistry reagent, featuring an azide group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with alkyne-containing molecules. Azido-PEG1-CH2CO2H is particularly useful in the synthesis of PROTACs, such as BRD4 Degrader-1, advancing research in targeted therapy and protein modulation.
Chemical Information
| Catalog Num | A81498 |
|---|---|
| M. Wt | 145.12 |
| Formula | C4H7N3O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 79598-48-4 |
| Synonyms | |
| SMILES | O=C(O)COCCN=[N+]=[N-] |
Biological Activity
| Description | Azido-PEG1-CH2CO2H is a PROTAC linker designed to facilitate targeted protein degradation through its alkyl/ether structure. This compound acts as a versatile click chemistry reagent, featuring an azide group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with alkyne-containing molecules. Azido-PEG1-CH2CO2H is particularly useful in the synthesis of PROTACs, such as BRD4 Degrader-1, advancing research in targeted therapy and protein modulation. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
