Product Data Sheet
endo-BCN-PEG2-NH2
Catalog No. A81526
endo-BCN-PEG2-NH2 is a PEG-based PROTAC linker designed to facilitate the synthesis of PROTAC molecules. It features a bicyclo[6.1.0]nonyne (BCN) group, enabling efficient strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with azide-bearing compounds. This linker is pivotal for advancing research in targeted protein degradation and optimizing the pharmacological profiles of novel therapeutic agents. Its utility in PROTAC development makes it an essential tool for scientists exploring innovative approaches in drug discovery and cellular regulation.
Chemical Information
| Catalog Num | A81526 |
|---|---|
| M. Wt | 324.42 |
| Formula | C17H28N2O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1263166-93-3 |
| Synonyms | |
| SMILES | NCCOCCOCCNC(OC[C@H]1[C@@]2([H])CCC#CCC[C@@]12[H])=O |
Biological Activity
| Description | endo-BCN-PEG2-NH2 is a PEG-based PROTAC linker designed to facilitate the synthesis of PROTAC molecules. It features a bicyclo[6.1.0]nonyne (BCN) group, enabling efficient strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with azide-bearing compounds. This linker is pivotal for advancing research in targeted protein degradation and optimizing the pharmacological profiles of novel therapeutic agents. Its utility in PROTAC development makes it an essential tool for scientists exploring innovative approaches in drug discovery and cellular regulation. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
