Product Data Sheet
3,6-Dioxaoctanedioic acid
Catalog No. A81555
3,6-Dioxaoctanedioic acid is a polyethylene glycol (PEG)-based PROTAC linker designed for the synthesis of PROTACs. This compound facilitates the development of targeted protein degradation mechanisms by linking E3 ligases to target proteins, thereby promoting their ubiquitination and subsequent proteasomal degradation. Its structural properties support effective binding and stability, making it a valuable reagent in research applications focused on targeted therapy and modalities in protein regulation.
Chemical Information
| Catalog Num | A81555 |
|---|---|
| M. Wt | 178.14 |
| Formula | C6H10O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 23243-68-7 |
| Synonyms | |
| SMILES | O=C(O)COCCOCC(O)=O |
Biological Activity
| Description | 3,6-Dioxaoctanedioic acid is a polyethylene glycol (PEG)-based PROTAC linker designed for the synthesis of PROTACs. This compound facilitates the development of targeted protein degradation mechanisms by linking E3 ligases to target proteins, thereby promoting their ubiquitination and subsequent proteasomal degradation. Its structural properties support effective binding and stability, making it a valuable reagent in research applications focused on targeted therapy and modalities in protein regulation. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
