Product Data Sheet

Azido-PEG12-acid

Catalog No. A81571

main product photo
Azido-PEG12-acid is a PEG-based PROTAC linker featuring an azide functional group, facilitating the synthesis of proteolysis-targeting chimeras (PROTACs). This compound is a key reagent for click chemistry applications, capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-bearing molecules and strain-promoted azide-alkyne cycloaddition (SPAAC) with DBCO or BCN substrates. Its utility in PROTAC development supports the advancement of targeted protein degradation research.
Chemical Information
Catalog NumA81571
M. Wt643.72
FormulaC27H53N3O14
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2152679-71-3
Synonyms
SMILESOC(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])=O
Biological Activity
DescriptionAzido-PEG12-acid is a PEG-based PROTAC linker featuring an azide functional group, facilitating the synthesis of proteolysis-targeting chimeras (PROTACs). This compound is a key reagent for click chemistry applications, capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-bearing molecules and strain-promoted azide-alkyne cycloaddition (SPAAC) with DBCO or BCN substrates. Its utility in PROTAC development supports the advancement of targeted protein degradation research.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.