Fmoc-7-amino-heptanoic acid
Catalog No. A81737

Fmoc-7-amino-heptanoic acid serves as a versatile PROTAC linker with a terminal Fmoc-protected amine and carboxylic acid functionalities. It facilitates the synthesis of PROTACs by allowing the deprotection of the Fmoc group under basic conditions, yielding a free amine suitable for additional conjugation reactions. The carboxylic acid is reactive towards primary amines in the presence of coupling agents, enabling the formation of stable amide bonds essential for constructing complex molecular architectures in chemical research.
Chemical Information
| Catalog Num | A81737 |
|---|---|
| M. Wt | 367.44 |
| Formula | C22H25NO4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 127582-76-7 |
| Synonyms | |
| SMILES | O=C(O)CCCCCCNC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O |
Biological Activity
| Description | Fmoc-7-amino-heptanoic acid serves as a versatile PROTAC linker with a terminal Fmoc-protected amine and carboxylic acid functionalities. It facilitates the synthesis of PROTACs by allowing the deprotection of the Fmoc group under basic conditions, yielding a free amine suitable for additional conjugation reactions. The carboxylic acid is reactive towards primary amines in the presence of coupling agents, enabling the formation of stable amide bonds essential for constructing complex molecular architectures in chemical research. |
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


