Product Data Sheet
Biotin-PEG6-NHS ester
Catalog No. A81747
Biotin-PEG6-NHS ester is a polyethylene glycol (PEG)-based linker specifically designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound allows for efficient conjugation to target proteins, facilitating the targeted degradation of specific intracellular proteins. Its biotin moiety enhances affinity for streptavidin or avidin, making it valuable in various biochemical assays and applications in drug discovery. This linker is essential for developing targeted therapeutics utilizing the PROTAC technology.
Chemical Information
| Catalog Num | A81747 |
|---|---|
| M. Wt | 676.78 |
| Formula | C29H48N4O12S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2055045-04-8 |
| Synonyms | |
| SMILES | O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCOCCOCCNC(CCCC[C@@H]2SC[C@]([C@]2([H])N3)([H])NC3=O)=O |
Biological Activity
| Description | Biotin-PEG6-NHS ester is a polyethylene glycol (PEG)-based linker specifically designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound allows for efficient conjugation to target proteins, facilitating the targeted degradation of specific intracellular proteins. Its biotin moiety enhances affinity for streptavidin or avidin, making it valuable in various biochemical assays and applications in drug discovery. This linker is essential for developing targeted therapeutics utilizing the PROTAC technology. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
