Product Data Sheet
Fmoc-12-aminododecanoic acid
Catalog No. A81762
Fmoc-12-aminododecanoic acid is a PROTAC linker characterized by an alkane chain with a terminal Fmoc-protected amine and a carboxylic acid group. This compound serves as a building block in the synthesis of PROTACs, facilitating targeted protein degradation studies. The Fmoc group can be readily deprotected in basic conditions, releasing a free amine for subsequent conjugations, while the terminal carboxylic acid allows for stable amide bond formation with primary amines using suitable coupling reagents.
Chemical Information
| Catalog Num | A81762 |
|---|---|
| M. Wt | 437.57 |
| Formula | C27H35NO4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 128917-74-8 |
| Synonyms | |
| SMILES | O=C(O)CCCCCCCCCCCNC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O |
Biological Activity
| Description | Fmoc-12-aminododecanoic acid is a PROTAC linker characterized by an alkane chain with a terminal Fmoc-protected amine and a carboxylic acid group. This compound serves as a building block in the synthesis of PROTACs, facilitating targeted protein degradation studies. The Fmoc group can be readily deprotected in basic conditions, releasing a free amine for subsequent conjugations, while the terminal carboxylic acid allows for stable amide bond formation with primary amines using suitable coupling reagents. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
