9-(Boc-amino)nonanoic acid
Catalog No. A81765

9-(Boc-amino)nonanoic acid functions as a PROTAC linker, featuring an alkane chain that contains a terminal carboxylic acid and a Boc-protected amino group. This compound is instrumental in the synthesis of PROTACs, as its carboxylic acid can efficiently react with primary amines in the presence of coupling agents, such as EDC or HATU, to yield stable amide bonds. The Boc protecting group can be removed under mild acidic conditions, resulting in the formation of the free amine, facilitating subsequent chemical modifications.
Chemical Information
| Catalog Num | A81765 |
|---|---|
| M. Wt | 273.37 |
| Formula | C14H27NO4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 173435-78-4 |
| Synonyms | |
| SMILES | O=C(O)CCCCCCCCNC(OC(C)(C)C)=O |
Biological Activity
| Description | 9-(Boc-amino)nonanoic acid functions as a PROTAC linker, featuring an alkane chain that contains a terminal carboxylic acid and a Boc-protected amino group. This compound is instrumental in the synthesis of PROTACs, as its carboxylic acid can efficiently react with primary amines in the presence of coupling agents, such as EDC or HATU, to yield stable amide bonds. The Boc protecting group can be removed under mild acidic conditions, resulting in the formation of the free amine, facilitating subsequent chemical modifications. |
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


