Product Data Sheet

Azido-PEG6-azide

Catalog No. A81814

main product photo
Azido-PEG6-azide is a PEG-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). Featuring an azide functional group, it facilitates click chemistry through copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with dibenzocyclooctyne (DBCO) or bicyclononyne (BCN) groups, making it a versatile tool for targeted protein degradation studies.
Chemical Information
Catalog NumA81814
M. Wt376.41
FormulaC14H28N6O6
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1243536-56-2
Synonyms
SMILES[N-]=[N+]=NCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]
Biological Activity
DescriptionAzido-PEG6-azide is a PEG-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). Featuring an azide functional group, it facilitates click chemistry through copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with dibenzocyclooctyne (DBCO) or bicyclononyne (BCN) groups, making it a versatile tool for targeted protein degradation studies.
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