Product Data Sheet
Boc-NH-PEG3-NHS ester
Catalog No. A82082
Boc-NH-PEG3-NHS ester is a polyethylene glycol (PEG)-derived PROTAC linker that facilitates the conjugation of target proteins to E3 ligases, enhancing proteasome-mediated degradation. This compound is essential in the development of PROTACs designed to manipulate protein levels within cells, offering significant potential for therapeutic applications in cancer and other diseases. Its ability to provide solubility and favorable pharmacokinetics makes it a valuable tool in chemical biology research.
Chemical Information
| Catalog Num | A82082 |
|---|---|
| M. Wt | 418.44 |
| Formula | C18H30N2O9 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2250216-93-2 |
| Synonyms | |
| SMILES | O=C(CCOCCOCCOCCNC(OC(C)(C)C)=O)ON(C1=O)C(CC1)=O |
Biological Activity
| Description | Boc-NH-PEG3-NHS ester is a polyethylene glycol (PEG)-derived PROTAC linker that facilitates the conjugation of target proteins to E3 ligases, enhancing proteasome-mediated degradation. This compound is essential in the development of PROTACs designed to manipulate protein levels within cells, offering significant potential for therapeutic applications in cancer and other diseases. Its ability to provide solubility and favorable pharmacokinetics makes it a valuable tool in chemical biology research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
